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(4-Propylphenyl)boronic acid → N-[5-(4-propylphenyl)thiophene-2-sulfonyl]pyrrole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (4-Propylphenyl)boronic acid | HCID 4100861 | — |
| 反応物 | N-(5-bromothiophenesulfonyl)pyrrole | HCID 23445587 | — |
| 生成物 | N-[5-(4-propylphenyl)thiophene-2-sulfonyl]pyrrole | HCID 22998454 | 55% |
反応手順
N-[5-(4-propylphenyl)thiophene-2-sulfonyl]pyrrole was prepared in the same manner as described in Example 33C, from 4-propylphenyl boronic acid and N-(5-bromothiophenesulfonyl)pyrrole. Purification by column chromatography using 10% ethyl acetate/hexanes gave the pure sulfonamide as a white solid in 55% yield, m.p. 106°-108° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05594021 |
| 出典データセット | uspto-grants-1997_01 |
| ORD ID | ord-8d293ef0b7d547b089e97ebbc157a920 |
| 出典メモ | uspto-grants-1997_01 |