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Chlorosulfonic acid → 2-Ethylbenzo[b]furan-3-sulfonyl chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Chlorosulfonic acid | HCID 24638 | — |
| 反応物 | Phosphorus pentachloride | HCID 24819 | — |
| 反応物 | 2-Ethylbenzofuran | HCID 76582 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 2-Ethylbenzo[b]furan-3-sulfonyl chloride | HCID 22998408 | — |
反応手順
2-Ethylbenzo[b]furan-3-sulfonyl chloride was prepared by the method of Example 82C with 2-ethylbenzo[b]furan (6.9 mmols, 1.0 g), chlorosulfonic acid (8.9 mmols, 0.6 ml) phosphorous oxychloride (21 mmols, 1.9 ml), phosphorous pentachloride (6.9 mmols, 1.4 g) and CH2Cl2 (10 ml). Flash chromatography (2% ethyl acetate/hexanes) provided 0.71 g (42%) of an orange solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05594021 |
| 出典データセット | uspto-grants-1997_01 |
| ORD ID | ord-6bbbd6bb37f840c49a7453d254ec080f |
| 出典メモ | uspto-grants-1997_01 |