Dimethylformamide → 4-(3-Chlorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid (3-imidazole-1-yl-propyl)amide

反応式

[Cl:1][c:2]1[cH:3][c:4]([CH:8]2[NH:9][C:10](=[O:18])[NH:11][C:12]([CH3:17])=[C:13]2[C:14](=[O:15])[OH:16])[cH:5][cH:6][cH:7]1.[NH2:19][CH2:20][CH2:21][CH2:22][n:23]1[cH:24][n:25][cH:26][cH:27]1.[O:28]=[CH:29][N:30]([CH3:31])[CH3:32]>>[Cl:1][c:2]1[cH:3][c:4]([CH:8]2[NH:9][C:10](=[O:18])[NH:11][C:12]([CH3:17])=[C:13]2[C:14](=[O:16])[NH:19][CH2:20][CH2:21][CH2:22][n:23]2[cH:24][n:25][cH:26][cH:27]2)[cH:5][cH:6][cH:7]1

参加物

反応物 3

HCID 6228Dimethylformamide

HCID 787361H-Imidazole-1-propanamine

HCID 225701824-(3-Chlorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid

生成物 1

HCID 207589074-(3-Chlorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid (3-imidazole-1-yl-propyl)amide

出典と根拠

ORDレコード: ord-23f85810b522463b99d9c433d8362fcb
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…