化工社化工社 化学情報印刷レポート · 研究参考用
2,4-Dinitrobenzoic acid → 2,4-Dinitrobenzamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2,4-Dinitrobenzoic acid | HCID 11880 | — |
| 反応物 | Ammonium Hydroxide | HCID 14923 | — |
| 反応物 | Oxalyl chloride | HCID 65578 | — |
| 生成物 | 2,4-Dinitrobenzamide | HCID 3733518 | 89% |
反応手順
2,4-Dinitrobenzoic acid (8.17 g, 38.5 mmol) was treated with oxalyl chloride (3.90 mL, 44.7 mmol). The resulting acid chloride was treated with saturated NH4OH solution (200 mL) to yield the title compound (7.25 g, 89%). m.p. 202°-204° C. 1H NMR (300 MHz, DMSO) δ8.75 (d, 1H), 8.58 (dd, 1H), 8.48 (br s, 1H), 7.99 (br s, 1H), 7.91 (d, 1H), 5.50-6.20 (br s, 2H). MS (DCI/NH3) m/e 229 (M+NH4)+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05597823 |
| 出典データセット | uspto-grants-1997_01 |
| ORD ID | ord-31a6f5a7f71c4d809ae281e01e1ca844 |
| 出典メモ | uspto-grants-1997_01 |