Aniline → Aniline, N-(2,2,2-trifluoroethyl)-

HRID 2351251

反応式

HRID 2351251 の反応式
FC(F)(F)S([O-])(=O)=O.[F:9][C:10]([F:20])([F:19])[CH2:11][I+]C1C=CC=CC=1.[NH2:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>C(Cl)Cl>[F:9][C:10]([F:20])([F:19])[CH2:11][NH:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1

参加物

4

反応物 2

HCID 6115AnilineHCID 10993805HCID 10993805、化合物

生成物 1

HCID 9596Aniline, N-(2,2,2-trifluoroethyl)-収率 90.8%

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

250 mg (0.573 mmol) of (2,2,2-trifluoroethyl)phenyliodonium trifluoromethanesulfonate, 107 mg (1.15 mmol) of aniline and 5 ml of methylene chloride were reacted and worked up in the same manner as described in Reference Example 4 to obtain 91.1 mg of N-(2,2,2-trifluoroethyl)aniline as an oily substance. Yield, 92%.

出典と根拠

ORDレコード
ord-5d456a4c84e6411aa1338919de3e5b1a
出典データセット
uspto-grants-1989_10
特許番号
US04873027

関連ノート

読み込み中…