Etofenprox → 3-Phenoxytoluene

HRID 2351806

反応式

HRID 2351806 の反応式
[CH2:1]([O:3][C:4]1[CH:9]=[CH:8][C:7]([C:10]([CH3:28])([CH3:27])[CH2:11][O:12][CH2:13][C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([O:20][C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)[CH:15]=2)=[CH:6][CH:5]=1)[CH3:2].ClC1C=C(C(C)(C)COCC2C=CC=C(OC3C=CC=CC=3)C=2)C=CC=1OCC>C1C=CC=CC=1>[O:20]([C:16]1[CH:15]=[C:14]([CH3:13])[CH:19]=[CH:18][CH:17]=1)[C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=1.[CH2:1]([O:3][C:4]1[CH:9]=[CH:8][C:7]([C:10]([CH3:27])([CH3:28])[CH2:11][OH:12])=[CH:6][CH:5]=1)[CH3:2]

参加物

5

反応物 2

HCID 71245EtofenproxHCID 30671833-Chloro-4-ethoxyneophyl 3-phenoxybenzyl ether

生成物 2

HCID 191653-PhenoxytolueneHCID 1585252-(4-Ethoxyphenyl)-2-methylpropanol

試薬・触媒・溶媒 1

HCID 241Benzene溶媒

反応条件

温度
50 °C

実験手順

The reaction mixture was cooled to 50° C. and the residual pressure was released, and 100 ml of benzene was added into the autoclave to dissolve the oil layer. Then, the catalyst was removed by filtration, and the filtrate was allowed to stand still to cause phase separation, and the benzene layer was recovered and washed with 120 ml of water three times, and benzene was removed by distillation under reduced pressure to give an oily product. From the results of the analysis of the oily product by gas chromatography according to the internal standard method, it was found that the oily product comprised 98.8% of 3-phenoxybenzyl 2-(4-ethoxyphenyl)-2-methylpropyl ether and 0.3% of unreacted starting 3-phenoxybenzyl 2-(3-chloro-4-ethoxyphenyl)-2-methylpropyl ether, and that the content of each of 3-phenoxytoluene and 4-ethoxyneophyl alcohol formed by cleaving of the ether linkage was lower than 0.3%. The amount of the obtained oily product was 53.8 g, and the yield was 96.7%.

後処理

  1. dissolutionto dissolve the oil layer
  2. customThen, the catalyst was removed by filtration
  3. customphase separation
  4. customthe benzene layer was recovered
  5. washwashed with 120 ml of water three times, and benzene
  6. customwas removed by distillation under reduced pressure
  7. customto give an oily product
  8. customFrom the results of the analysis of the oily product by gas chromatography

出典と根拠

ORDレコード
ord-413d38bb0cd042b7b6e224623631a215
出典データセット
uspto-grants-1989_10
特許番号
US04873373

関連ノート

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