Pyruvic Acid → 2-[2-(4-Chlorophenyl)hydrazinylidene]propanoic acid

HRID 235616

反応式

HRID 235616 の反応式
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][NH2:9])=[CH:4][CH:3]=1.[C:10]([OH:15])(=[O:14])[C:11]([CH3:13])=O>O>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][N:9]=[C:11]([CH3:13])[C:10]([OH:15])=[O:14])=[CH:4][CH:3]=1

参加物

4

反応物 2

HCID 1060Pyruvic AcidHCID 70624(4-Chlorophenyl)hydrazine

生成物 1

HCID 2284632-[2-(4-Chlorophenyl)hydrazinylidene]propanoic acid

試薬・触媒・溶媒 1

HCID 962Water溶媒

反応条件

温度
70 °C

実験手順

75.7 g of hydrochloric salt of parachlorophenylhydrazine was dissolved into 350 ml of water. 37.2 g of pyruvic acid was added into the solution. After stirring for 30 minutes at 70° C. while heating, and then cooling, precipitated crystals were filtered out, washed, and dried. These crystals were recrystallized from isopropyl acohol to obtain 57 g of 2-(p-chlorophenylhydrazono)propionic acid having a melting point of 196° to 197° C. (decomposed).

後処理

  1. temperaturewhile heating
  2. temperaturecooling
  3. customprecipitated crystals
  4. filtrationwere filtered out
  5. washwashed
  6. customdried
  7. customThese crystals were recrystallized from isopropyl acohol

出典と根拠

ORDレコード
ord-e983d2b21ed74c50872c53dbc60acdb2
出典データセット
uspto-grants-1987_02
特許番号
US04640892

関連ノート

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