Dimethylformamide → N-(3-fluoro-4-(isoquinolin-5-yl)phenyl)-1-((S)-2-hydroxypropyl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide

反応式

[F:1][C:2]1[CH:3]=[C:4]([NH2:18])[CH:5]=[CH:6][C:7]=1[C:8]1[CH:17]=[CH:16][CH:15]=[C:14]2[C:9]=1[CH:10]=[CH:11][N:12]=[CH:13]2.[OH:19][C@@H:20]([CH3:38])[CH2:21][N:22]1[C:26]([CH3:27])=[C:25]([C:28](O)=[O:29])[C:24](=[O:31])[N:23]1[C:32]1[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=1.CN(C=O)C>C(Cl)Cl>[F:1][C:2]1[CH:3]=[C:4]([NH:18][C:28]([C:25]2[C:24](=[O:31])[N:23]([C:32]3[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=3)[N:22]([CH2:21][C@@H:20]([OH:19])[CH3:38])[C:26]=2[CH3:27])=[O:29])[CH:5]=[CH:6][C:7]=1[C:8]1[CH:17]=[CH:16][CH:15]=[C:14]2[C:9]=1[CH:10]=[CH:11][N:12]=[CH:13]2