Hydrochloric Acid → HCID 69731619、化合物
反応式
C(OC([NH:8][CH2:9][C:10]1[CH:15]=[CH:14][C:13]([CH:16]([CH2:20][CH:21]=[CH2:22])[C:17]([OH:19])=[O:18])=[CH:12][CH:11]=1)=O)(C)(C)C.Cl.[CH3:24]O>C(OCC)C>[CH3:24][O:19][C:17](=[O:18])[CH:16]([C:13]1[CH:14]=[CH:15][C:10]([CH2:9][NH2:8])=[CH:11][CH:12]=1)[CH2:20][CH:21]=[CH2:22]参加物
5
実験手順
To a stirred solution of commercially available (Astatech) 2-[4-(tert-butoxycarbonylamino-methyl)-phenyl]-pent-4-enoic acid (2.00 g, 6.55 mmol) in methanol (30 cm3) under an atmosphere of dry nitrogen at ambient temperature was added 2M HCl in diethyl ether. The solution was stirred at ambient temperature for 20 hours and the filtrate volatile fractions removed in vacuo to afford the title compound as a white solid (1.67 g, 99.9%) with a positive ion ESI (M+H)+219.2.
後処理
- customthe filtrate volatile fractions removed in vacuo
出典と根拠
- ORDレコード
- ord-0acf6193c67e47f58731abf98e40c792
- 出典データセット
- uspto-grants-2005_02
- 特許番号
- US06852713B2
反応ノート
読み込み中…