Hydrochloric Acid → N-(4-methanesulfonylamino-3-vinyl-benzyl)-2,3-diphenyl-propionamide

HRID 2358426

反応式

HRID 2358426 の反応式
[CH3:1][S:2]([NH:5][C:6]1[CH:13]=[CH:12][C:9]([CH2:10][NH2:11])=[CH:8][C:7]=1[CH:14]=[CH2:15])(=[O:4])=[O:3].Cl.[C:17]1([C:23](=[CH:27][C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)[C:24](O)=[O:25])[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[CH3:1][S:2]([NH:5][C:6]1[CH:13]=[CH:12][C:9]([CH2:10][NH:11][C:24](=[O:25])[CH:23]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[CH2:27][C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)=[CH:8][C:7]=1[CH:14]=[CH2:15])(=[O:4])=[O:3]

参加物

4

反応物 3

HCID 313Hydrochloric AcidHCID 66677alpha,beta-Diphenyl acrylic acidHCID 57665523N-(4-aminomethyl-2-vinylphenyl)methanesulfonamide

生成物 1

HCID 68453616N-(4-methanesulfonylamino-3-vinyl-benzyl)-2,3-diphenyl-propionamide収率 68%

実験手順

4-Methanesulfonylamino-3-vinylbenzylamine and HCl salt (131 mg, 0.499 mmol) were reacted with 2,3-diphenyl-acrylic acid (115 mg, 0.512 mmol) prepared by the reported procedure to give N-(4-methanesulfonylamino-3-vinyl-benzyl)-2,3-diphenyl-propionamide (146 mg, 68%).

後処理

  1. customprepared by the reported procedure

出典と根拠

ORDレコード
ord-b3aa2419e96f4133b48f59ce575eeae3
出典データセット
uspto-grants-2010_07
特許番号
US07763657B2

関連ノート

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