化工社化工社 化学情報印刷レポート · 研究参考用
Hydrochloric Acid → 2-(3-Methoxyphenyl)cyclopropane-1-carboxylic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Cyclopropanecarboxylic acid, 2-(3-methoxyphenyl)-, ethyl ester | HCID 19358490 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 溶媒 | Sodium Hydroxide | HCID 14798 | — |
| 生成物 | 2-(3-Methoxyphenyl)cyclopropane-1-carboxylic acid | HCID 13972233 | — |
反応手順
The crude 2-(3-methoxy-phenyl)-cyclopropanecarboxylic acid ethyl ester is dissolved in 30 ml EtOH and 15 ml 1N NaOH. After stirring over night, the reaction mixture is acidified with 1N HCl and extracted with diethyl ether. After removal of the solvent 7.1 g of the 2-(3-methoxy-phenyl)-cyclopropanecarboxylic acid is obtained. This 2-(3-methoxy-phenyl)-cyclopropanecarboxylic acid is used without further purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07763728B2 |
| 出典データセット | uspto-grants-2010_07 |
| ORD ID | ord-115159adedc34e79819ccca64391392a |
| 出典メモ | uspto-grants-2010_07 |