Phosphorus oxychloride → 4-Chloro-2,7-dimethyl-[1,8]naphthyridine
反応式
[CH3:1][C:2]1[NH:3][C:4]2[C:9]([C:10](=O)[CH:11]=1)=[CH:8][CH:7]=[C:6]([CH3:13])[N:5]=2.O=P(Cl)(Cl)[Cl:16]>>[Cl:16][C:10]1[C:9]2[C:4](=[N:5][C:6]([CH3:13])=[CH:7][CH:8]=2)[N:3]=[C:2]([CH3:1])[CH:11]=1参加物
3
実験手順
The product from Example 14a (500 mg, 2.87 mmol) was reacted with 10 mL of POCl3 for 2 h following the procedure from Example 1d giving the title compound, which was used without purification.
出典と根拠
- ORDレコード
- ord-443155a58a9c4af0b5e3f186a747dda1
- 出典データセット
- uspto-grants-2010_07
- 特許番号
- US07763731B2
反応ノート
読み込み中…