4-Bromobenzyl bromide → 4-(4-Bromo-benzyloxy)-1-chloro-2-nitro-benzene

反応式

[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][C:3]=1[N+:9]([O-:11])=[O:10].[Br:12][C:13]1[CH:18]=[CH:17][C:16]([CH2:19]Br)=[CH:15][CH:14]=1>>[Br:12][C:13]1[CH:18]=[CH:17][C:16]([CH2:19][O:8][C:5]2[CH:6]=[CH:7][C:2]([Cl:1])=[C:3]([N+:9]([O-:11])=[O:10])[CH:4]=2)=[CH:15][CH:14]=1

参加物

反応物 2

HCID 685274-Bromobenzyl bromide

HCID 691274-Chloro-3-nitrophenol

生成物 1

HCID 574698834-(4-Bromo-benzyloxy)-1-chloro-2-nitro-benzene

実験手順

A solution of 4-chloro-3-nitro-phenol was reacted with 1-Bromo-4-bromomethyl-benzene using the conditions described in Example 237C to provide 4-(4-Bromo-benzyloxy)-1-chloro-2-nitro-benzene which was treated sequentially using the procedures from Examples 237D and 237E to provide the title product.

出典と根拠

ORDレコード: ord-7dd25a81d4194dc892ba3d975de7cfd7
出典データセット: uspto-grants-2010_07
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07763731B2

反応ノート

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