Benzoyl chloride → N-[2-(Furan-3-yl)-2-oxoethyl]benzamide

反応式

Cl.[O:2]1[CH:6]=[CH:5][C:4]([C:7]([CH2:9][NH2:10])=[O:8])=[CH:3]1.C(=O)(O)[O-].[Na+].[C:16](Cl)(=[O:23])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[C:16]([NH:10][CH2:9][C:7]([C:4]1[CH:5]=[CH:6][O:2][CH:3]=1)=[O:8])(=[O:23])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1

参加物

反応物 3

HCID 7412Benzoyl chloride

HCID 516892Sodium Bicarbonate

HCID 137731212-Amino-1-(furan-3-yl)ethan-1-one--hydrogen chloride (1/1)

生成物 1

HCID 13773129N-[2-(Furan-3-yl)-2-oxoethyl]benzamide収率 91.8%

実験手順

6.0 g of (3-furylcarbonyl)methylamine hydrochloride, 7.8 g of sodium bicarbonate and 5.7 g of benzoyl chloride are treated in the same manner as described in Preparation 1-(1). 7.8 g of N-benzoyl-(3-furylcarbonyl)methylamine are thereby obtained. Yield: 91.8%

後処理

customas described in Preparation 1-(1)

出典と根拠

ORDレコード: ord-9c2894dd6ef646048673f0d55cc00d38
出典データセット: uspto-grants-1987_02
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04642313

反応ノート

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