Benzene, 1-chloro-3-isocyanato- → 1-(3-Chlorophenyl)imidazolidin-2-one
反応式
[Cl:1][C:2]1[CH:3]=[C:4]([N:8]=[C:9]=[O:10])[CH:5]=[CH:6][CH:7]=1.O1[CH2:15][CH2:14][NH:13]C1=O.[Al+3].[Cl-].[Cl-].[Cl-]>ClCCl>[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[CH2:15][CH2:14][NH:13][C:9]2=[O:10])[CH:5]=[CH:6][CH:7]=1参加物
5
反応条件
- 温度
- 195 °C
実験手順
A mixture of 3-chlorophenyl isocyanate (50 mmoles), 2-oxazolidinone (50 mmoles) and anhydrous AlCl3 (40 mg, 0.3 mmole) is heated at 195° C. for 6 hours with stirring. The reaction mixture is dissolved in dichloromethane and the resulting solution is washed with water twice. The dichloromethane solution is dried and evaporated and the residue distilled at reduced pressure. The distillate is recrystallized from hot hexane to give a yield of 74 percent of the desired product, m.p. 121° C.-123° C.
後処理
- washthe resulting solution is washed with water twice
- dry with materialThe dichloromethane solution is dried
- customevaporated
- distillationthe residue distilled at reduced pressure
- customThe distillate is recrystallized from hot hexane
出典と根拠
- ORDレコード
- ord-49e9d5a146a249c7b0465e8d85ac2964
- 出典データセット
- uspto-grants-1987_02
- 特許番号
- US04642351
反応ノート
読み込み中…