4-Phenoxyphenyl isocyanate → 1-Benzylindolin-5-yl 4-phenoxyphenylcarbamate

反応式

[CH2:1]([N:8]1[C:16]2[C:11](=[CH:12][C:13]([OH:17])=[CH:14][CH:15]=2)[CH2:10][CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[O:18]([C:25]1[CH:30]=[CH:29][C:28]([N:31]=[C:32]=[O:33])=[CH:27][CH:26]=1)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>>[O:18]([C:25]1[CH:26]=[CH:27][C:28]([NH:31][C:32](=[O:33])[O:17][C:13]2[CH:12]=[C:11]3[C:16](=[CH:15][CH:14]=2)[N:8]([CH2:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)[CH2:9][CH2:10]3)=[CH:29][CH:30]=1)[C:19]1[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=1

参加物

反応物 2

HCID 27348964-Phenoxyphenyl isocyanate

HCID 866598571-Benzylindolin-5-ol

生成物 1

HCID 866598611-Benzylindolin-5-yl 4-phenoxyphenylcarbamate

実験手順

The title compound was synthesized from 1-benzylindolin-5-ol (35.0 mg, 0.155 mmol) using the same procedure employed for Example 2 (2), but with 4-phenoxyphenylisocyanate instead of 4-isopropylphenylisocyanate. The product was obtained as a white solid (7.4 mg, 11%) having the following characteristics.

出典と根拠

ORDレコード: ord-124eeba153f040eebd301b0cfc765219
出典データセット: uspto-grants-2014_04
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08686024B2

反応ノート

読み込み中…