5-Isocyanato-2,3-dihydro-1-benzofuran → 1-Benzylindolin-5-yl 2,3-dihydro-1-benzofuran-5-ylcarbamate
反応式
[CH2:1]([N:8]1[C:16]2[C:11](=[CH:12][C:13]([OH:17])=[CH:14][CH:15]=2)[CH2:10][CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[O:18]1[C:22]2[CH:23]=[CH:24][C:25]([N:27]=[C:28]=[O:29])=[CH:26][C:21]=2[CH2:20][CH2:19]1>>[O:18]1[C:22]2[CH:23]=[CH:24][C:25]([NH:27][C:28](=[O:29])[O:17][C:13]3[CH:12]=[C:11]4[C:16](=[CH:15][CH:14]=3)[N:8]([CH2:1][C:2]3[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=3)[CH2:9][CH2:10]4)=[CH:26][C:21]=2[CH2:20][CH2:19]1参加物
3
実験手順
The title compound was synthesized from 1-benzylindolin-5-ol (35.0 mg, 0.155 mmol) using the same procedure employed for Example 2 (2), but with 2,3-dihydro-1-benzofuran-5-ylisocyanate instead of 4-isopropylphenylisocyanate. The product was obtained as a white solid (9.0 mg, 13%) having the following characteristics.
出典と根拠
- ORDレコード
- ord-10a3580c39b043c3906d22a2d4892ccf
- 出典データセット
- uspto-grants-2014_04
- 特許番号
- US08686024B2
反応ノート
読み込み中…