関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Pyridine | HCID 1049 | — |
| 反応物 | Acetyl chloride | HCID 6367 | — |
| 反応物 | Ameltolide | HCID 13086 | — |
| 溶媒 | Water | HCID 962 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 4-(acetylamino)-N-(2,6-dimethylphenyl)benzamide | HCID 443227 | 85% |
反応手順
To a solution of 2.0 g of 4-amino-N-(2,6-dimethylphenyl)benzamide in dimethylformamide were added 1 ml of pyridine followed by 710 μl of acetyl chloride. The reaction was stirrred at room temperature for 2 hours, diluted with water, and chilled to approximately 4° C. The title product was recovered by filtration in 85% yield, m.p. 293°-295° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04642379 |
|---|
| 出典データセット | uspto-grants-1987_02 |
|---|
| ORD ID | ord-0da184272f6b474bb5fac4687f8f7171 |
|---|
| 出典メモ | uspto-grants-1987_02 |
|---|
