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Diethanolamine → HCID 22590162、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Diethanolamine | HCID 8113 | — |
| 反応物 | 4-Fluoro-3-(trifluoromethyl)benzonitrile | HCID 144255 | — |
| 溶媒 | Dimethylacetamide | HCID 31374 | — |
| 生成物 | HCID 22590162 | HCID 22590162 | — |
反応手順
A solution of 3-trifluoromethyl 4-fluoro-benzonitrile (9.45 g, 50 mmol) and diethanolamine (15.8 g, 0.15 mol) in N,N-dimethylacetamide (200 ml) was stirred for 7 days at 50° C. The solvent was evaporated, the residue partitioned between CH2Cl2 (400 ml) and H2O (400 ml), the organic layer dried (MgSO4) and evaporated to dryness. The residue was chromatographed using CH2Cl2-EtOH as eluent.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06852755B1 |
| 出典データセット | uspto-grants-2005_02 |
| ORD ID | ord-02ab42cfd43b416bbf1faed23df2983f |
| 出典メモ | uspto-grants-2005_02 |