化工社化工社 化学情報印刷レポート · 研究参考用
Iodine → N-methyl-N-p-chlorobenzyl-m-fluoroaniline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Iodine | HCID 807 | — |
| 反応物 | 1-Chloro-4-(chloromethyl)benzene | HCID 7723 | — |
| 反応物 | Sodium Acetate | HCID 517045 | — |
| 反応物 | 3-fluoro-N-methylaniline | HCID 2759011 | — |
| 生成物 | N-methyl-N-p-chlorobenzyl-m-fluoroaniline | HCID 14008649 | — |
反応手順
N-methyl-N-p-chlorobenzyl-m-fluoroaniline was prepared from 17.5 grams (0.14 mole) of N-methyl-m-fluoroaniline, 23.7 grams (0.14 mole) p-chlorobenzyl chloride (Aldrich), 11.9 grams anhydrous sodium acetate and 0.12 grams iodine according to the procedure as described in Example III. Yield 25.8 grams (74 percent), boiling point 162°-170° C. at 0.13 mmHg.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04644082 |
| 出典データセット | uspto-grants-1987_02 |
| ORD ID | ord-ec17b135791349aa87589d5aa58776f1 |
| 出典メモ | uspto-grants-1987_02 |