化工社化工社 化学情報印刷レポート · 研究参考用
Iodine → N-methyl-N-p-fluorobenzyl-m-fluoroaniline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Iodine | HCID 807 | — |
| 反応物 | 4-Fluorobenzyl chloride | HCID 9602 | — |
| 反応物 | Sodium Acetate | HCID 517045 | — |
| 反応物 | 3-fluoro-N-methylaniline | HCID 2759011 | — |
| 生成物 | N-methyl-N-p-fluorobenzyl-m-fluoroaniline | HCID 14008648 | — |
反応手順
N-methyl-N-p-fluorobenzyl-m-fluoroaniline was prepared from 26.3 grams (0.21 mole) of N-methyl-m-fluoroaniline, 30.6 grams (0.21 mole) p-fluorobenzyl chloride (Aldrich), 17.8 grams anhydrous sodium acetate and 0.18 grams iodine according to the procedure described in Example III. Yield 35.4 grams (72 percent), boiling point 131°-137° C. at 0.2 mmHg.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04644082 |
| 出典データセット | uspto-grants-1987_02 |
| ORD ID | ord-f36b6624f57e45398122bca061dd5660 |
| 出典メモ | uspto-grants-1987_02 |