(S)-4-((2,6-dimethoxyphenoxy)methyl)-2,2-dimethyl-1,3-dioxolane → (R)-3-(2,6-Dimethoxyphenoxy)propane-1,2-diol
反応式
[CH3:1][O:2][C:3]1[CH:17]=[CH:16][CH:15]=[C:14]([O:18][CH3:19])[C:4]=1[O:5][CH2:6][C@H:7]1[CH2:11][O:10]C(C)(C)[O:8]1>CO>[CH3:19][O:18][C:14]1[CH:15]=[CH:16][CH:17]=[C:3]([O:2][CH3:1])[C:4]=1[O:5][CH2:6][C@H:7]([OH:8])[CH2:11][OH:10]参加物
3
実験手順
A mixture of (S)-4-((2,6-dimethoxyphenoxy)methyl)-2,2-dimethyl-1,3-dioxolane (2.91 g, 10.85 mmol) and Amberlyst 15® (1.60 g) in methanol (30 ml) were stirred for 5 d. The mixture was filtered and evaporated to dryness to give 2.26 g of the title compound.
後処理
- filtrationThe mixture was filtered
- customevaporated to dryness
出典と根拠
- ORDレコード
- ord-2b6f68e1adfb45508905cd02877fcd62
- 出典データセット
- uspto-grants-2014_04
- 特許番号
- US08697723B2
反応ノート
読み込み中…