Hydrochloric Acid → HCID 67228720、化合物
反応式
[ClH:1].[CH3:2][O:3][C:4]1[CH:5]=[C:6](/[C:12](=[CH:15]/[C:16]2[O:17][C:18]([N:21]([CH2:23][CH2:24][N:25]([CH3:27])[CH3:26])[CH3:22])=[CH:19][CH:20]=2)/[C:13]#[N:14])[CH:7]=[CH:8][C:9]=1[O:10][CH3:11]>>[ClH:1].[CH3:2][O:3][C:4]1[CH:5]=[C:6](/[C:12](=[CH:15]/[C:16]2[O:17][C:18]([N:21]([CH2:23][CH2:24][N:25]([CH3:27])[CH3:26])[CH3:22])=[CH:19][CH:20]=2)/[C:13]#[N:14])[CH:7]=[CH:8][C:9]=1[O:10][CH3:11]参加物
3
実験手順
0.1N Hydrochloric acid (12.5 mL) was added to Compound 48 (404 mg) for dissolution, and purified water (20 mL) was added to the solution, followed by stirring at room temperature for 20 minutes. The reaction mixture was lyophilized, to thereby yield the target product (yield: 400 mg, 90%).
後処理
- custompurified water (20 mL)
- additionwas added to the solution
出典と根拠
- ORDレコード
- ord-e895fcf375904a93bf956ac72a212cb4
- 出典データセット
- uspto-grants-2014_04
- DOI