3,4-Dimethoxybenzeneacetonitrile → (Z)-2-(3,4-dimethoxy-phenyl)-3-phenanthren-9-yl-acrylonitrile

反応式

[CH:1]1[C:14]2[CH:13]=[C:12]([CH:15]=O)[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:5]=2[CH:4]=[CH:3][CH:2]=1.[CH3:17][O:18][C:19]1[CH:20]=[C:21]([CH:25]=[CH:26][C:27]=1[O:28][CH3:29])[CH2:22][C:23]#[N:24]>>[CH3:17][O:18][C:19]1[CH:20]=[C:21](/[C:22](=[CH:15]/[C:12]2[C:11]3[C:6]([C:5]4[CH:4]=[CH:3][CH:2]=[CH:1][C:14]=4[CH:13]=2)=[CH:7][CH:8]=[CH:9][CH:10]=3)/[C:23]#[N:24])[CH:25]=[CH:26][C:27]=1[O:28][CH3:29]

参加物

反応物 2

HCID 667273,4-Dimethoxybenzeneacetonitrile

HCID 78437Phenanthrene-9-carbaldehyde

生成物 1

HCID 11964784(Z)-2-(3,4-dimethoxy-phenyl)-3-phenanthren-9-yl-acrylonitrile収率 63%

実験手順

Phenanthrene-9-aldehyde (250 mg) was condensed with 3,4-dimethoxybenzyl cyanide (214 mg) through Method A (production step 2), to thereby yield the target product (yield: 278 mg, 63%).

出典と根拠

ORDレコード: ord-6fae2bfe641e4e7e920b97f5be6c9f0d
出典データセット: uspto-grants-2014_04
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08697742B2

反応ノート

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