Dimethylformamide dimethyl acetal → HCID 67458045、化合物

反応式

[CH3:1][C:2]1([CH3:10])[CH2:7][CH2:6][C:5](=[O:8])[CH2:4][C:3]1=[O:9].CO[CH:13](OC)[N:14]([CH3:16])[CH3:15]>>[CH3:13][N:14]([CH:16]=[C:4]1[C:3](=[O:9])[C:2]([CH3:10])([CH3:1])[CH2:7][CH2:6][C:5]1=[O:8])[CH3:15]

参加物

反応物 2

HCID 78373Dimethylformamide dimethyl acetal

HCID 1363601,3-Cyclohexanedione, 4,4-dimethyl-

生成物 1

HCID 67458045HCID 67458045、化合物収率 95.5%

実験手順

According to Scheme 2 Step 1: A solution of 4,4-dimethylcyclohexane-1,3-dione (157 mmol, 22 g) and of 1,1-dimethoxy-N,N-dimethylmethanamine (235 mmol, 31.3 mL) was stirred at room temperature for 1 hour. After evaporation and trituration in petroleum ether, 29.2 g (150 mmol, 95%) of 2-((dimethylamino)methylene)-4,4-dimethylcyclohexane-1,3-dione were obtained as a pale orange solid.

後処理

customAfter evaporation and trituration in petroleum ether

出典と根拠

ORDレコード: ord-4ff6fdabbdf143b18a027c927ce7073c
出典データセット: uspto-grants-2014_04
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08697744B2

反応ノート

読み込み中…

参加物