Hydrogen chloride-ethyl acetate → HCID 67449164、化合物

HRID 2368083ノート

反応式

HRID 2368083 の反応式
[C:1]([NH:4][CH:5]([CH3:21])[CH2:6][CH2:7][CH:8]1[CH2:13][CH2:12][N:11](C(OC(C)(C)C)=O)[CH2:10][CH2:9]1)(=[O:3])[CH3:2].[ClH:22].C(OCC)(=O)C>C(OCC)(=O)C>[ClH:22].[CH3:21][CH:5]([NH:4][C:1](=[O:3])[CH3:2])[CH2:6][CH2:7][CH:8]1[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]1

参加物

4

反応物 2

HCID 21866389Hydrogen chloride-ethyl acetateHCID 67447123HCID 67447123、化合物

生成物 1

HCID 67449164HCID 67449164、化合物

試薬・触媒・溶媒 1

HCID 8857Ethyl Acetate溶媒

実験手順

To a solution of tert-butyl 4-[3-(acetylamino)butyl]piperidine-1-carboxylate (2.65 g) in ethyl acetate (30 mL) was added 4 M hydrogen chloride/ethyl acetate (10 mL), and the mixture was stirred at room temperature for 3 hr. The resulting precipitate was collected by filtration to give the title compound (2.06 g).

後処理

  1. filtrationThe resulting precipitate was collected by filtration

出典と根拠

ORDレコード
ord-0581df7d97994bf98d75189e57ceff52
出典データセット
uspto-grants-2014_04
特許番号
US08703758B2

反応ノート

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