化工社化工社 化学情報印刷レポート · 研究参考用
Diethyl Oxalate → rac-2-(1-Phenoxy-ethyl)-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyrazine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Diethyl Oxalate | HCID 7268 | — |
| 反応物 | 3-Phenoxy-2-butanone | HCID 2764474 | — |
| 反応物 | 2,4-Dioxo-5-phenoxy-pentanoic acid ethyl ester | HCID 57435086 | — |
| 反応物 | ethyl 1-{2-[(tert-butoxycarbonyl)amino]propyl}-3-(phenoxymethyl)-1H-pyrazole-5-carboxylate | HCID 67958408 | — |
| 反応物 | rac-6-methyl-2-phenoxymethyl-6,7-dihydro-5H-pyrazolo[1,5-a]pyrazin-4-one | HCID 67960066 | — |
| 反応物 | Rac-6-methyl-2-phenoxymethyl-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyrazine | HCID 67960219 | — |
| 反応物 | HCID 178469067 | HCID 178469067 | — |
| 生成物 | rac-2-(1-Phenoxy-ethyl)-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyrazine | HCID 67968152 | — |
反応手順
The compound was prepared from 3-phenoxy-butan-2-one and diethyl oxalate using the methods described in the preceding examples 9 (2,4-dioxo-5-phenoxy-pentanoic acid ethyl ester), 10 (5-phenoxymethyl-2H-pyrazole-3-carboxylic acid ethyl ester), 11 (rac-2-(2-tert-butoxycarbonylamino-propyl)-5-phenoxymethyl-2H-pyrazole-3-carboxylic acid ethyl ester), 12 (rac-6-methyl-2-phenoxymethyl-6,7-dihydro-5H-pyrazolo[1,5-a]pyrazin-4-one), and 13 (rac-6-methyl-2-phenoxymethyl-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyrazine).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08703946B2 |
| 出典データセット | uspto-grants-2014_04 |
| ORD ID | ord-dc1efb89c4d641b887a2598706db7c49 |
| 出典メモ | uspto-grants-2014_04 |