(3-Aminopropyl)triethoxysilane → alpha-D-Mannopyranose

HRID 2369766

反応式

HRID 2369766 の反応式
C1(NC2C(=O)C(=O)C=2)C=CC=CC=1.[OH:14][C@H:15]1[O:23][C@H:22]([CH2:24][OH:25])[C@@H:20]([OH:21])[C@H:18]([OH:19])[C@@H:16]1[OH:17].NCCC[Si](OCC)(OCC)OCC>C(O)C.O.C(N(CC)CC)C.CCO>[OH:14][C@H:15]1[O:23][C@H:22]([CH2:24][OH:25])[C@@H:20]([OH:21])[C@H:18]([OH:19])[C@@H:16]1[OH:17]

参加物

6

反応物 2

HCID 13521(3-Aminopropyl)triethoxysilaneHCID 86678081alpha-Mannose phenylaminocyclobutenedione2 回

生成物 1

HCID 185698alpha-D-Mannopyranose

試薬・触媒・溶媒 3

HCID 702Ethanol溶媒HCID 8471Triethylamine溶媒HCID 19096565Water ethanol溶媒

実験手順

α-mannose phenylaminocyclobutenedione (250 mg; 0.37 mmol) was dissolved in a mixture of Ethanol/H2O (3/2) (10 mL) and triethyamine (400 μL) was added dropwise to the solution of APTS (Aminopropyltriethoxysilane) grafted nanoparticles DB060 (250 mg in 10 ml of EtOH). The mixture was stirred during 16 h. The nanoparticles were then centrifugated and washed with water and ethanol and dried under vacuum to afford 232 mg of grafted nanoparticles. The concentration of α-mannose phenylaminocyclobutenedione grafted on the surface of the DB103 nanoaprticle is 0.089 mmol/g.

後処理

  1. washwashed with water and ethanol
  2. customdried under vacuum
  3. customto afford 232 mg of grafted nanoparticles

出典と根拠

ORDレコード
ord-b8eeaa78aaa64ca1b8ddeca525e5f66a
出典データセット
uspto-grants-2014_04
特許番号
US08709747B2

関連ノート

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