Tetrafluoroethylene → 4,5-bis-(2-furyl)-2-(1,1,2,2-tetrafluoroethylthio)-1H-imidazole

反応式

[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[N:7]=[C:8]([SH:16])[NH:9][C:10]=1[C:11]1[O:12][CH:13]=[CH:14][CH:15]=1.[F:17][C:18]([F:22])=[C:19]([F:21])[F:20]>>[O:12]1[CH:13]=[CH:14][CH:15]=[C:11]1[C:10]1[N:9]=[C:8]([S:16][C:19]([F:21])([F:20])[CH:18]([F:22])[F:17])[NH:7][C:6]=1[C:2]1[O:1][CH:5]=[CH:4][CH:3]=1

参加物

反応物 2

HCID 8301Tetrafluoroethylene

HCID 178527844HCID 178527844、化合物

生成物 1

HCID 213149894,5-bis-(2-furyl)-2-(1,1,2,2-tetrafluoroethylthio)-1H-imidazole収率 22.9%

実験手順

4,5-bis-(2-Furyl)-1H-2-imidazolethiol (8.1 g; 39.4 mmoles) was reacted with 7.0 g of tetrafluoroethylene and the product purified by chromatography on Silicar CCNo. 7 with chloroform to give 3.0 g of 4,5-bis-(2-furyl)-2-(1,1,2,2-tetrafluoroethylthio)-1H-imidazole, m.p. 166°-167°: (recrystallized from 1-chlorobutane).

後処理

customthe product purified by chromatography on Silicar CCNo

出典と根拠

ORDレコード: ord-a6ea955a832e4eb59acbb5ff9dd5339b
出典データセット: uspto-grants-1979_06
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04159338

反応ノート

読み込み中…

参加物