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2-Chloro-4,6-dimethylpyrimidine → 1-[(4,6-Dimethyl-2-pyrimidinyl)]-4-[[4-[[7-chloro-4-quinolinyl]amino]phenyl]sulfonyl]piperazine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Chloro-4,6-dimethylpyrimidine | HCID 20550 | — |
| 反応物 | [[4-[(7-Chloro-4-quinolinyl)amino]phenyl]sulfonyl]piperazine | HCID 54297387 | — |
| 生成物 | 1-[(4,6-Dimethyl-2-pyrimidinyl)]-4-[[4-[[7-chloro-4-quinolinyl]amino]phenyl]sulfonyl]piperazine | HCID 21314934 | — |
反応手順
In the manner given in Example 9, part E, 2-chloro-4,6-dimethylpyrimidine is heated with [[4-[(7-chloro-4-quinolinyl)amino]phenyl]sulfonyl]piperazine to give 1-[(4,6-dimethyl-2-pyrimidinyl)]-4-[[4-[[7-chloro-4-quinolinyl]amino]phenyl]sulfonyl]piperazine.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04159331 |
| 出典データセット | uspto-grants-1979_06 |
| ORD ID | ord-a4e7b78715994fb29acec40919aa7af3 |
| 出典メモ | uspto-grants-1979_06 |