HCID 46945366、化合物 → HCID 46945367、化合物

反応式

[CH3:1][C:2]1([CH3:43])[N:6]([CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][S:16]([CH2:18][CH2:19][CH2:20][C:21]([F:27])([F:26])[C:22]([F:25])([F:24])[F:23])=[O:17])[C:5](=[O:28])[N:4]([C:29]2[CH:34]=[CH:33][C:32]([N+:35]([O-])=O)=[C:31]([C:38](F)(F)F)[CH:30]=2)[C:3]1=[O:42].NC1C=CC(N2C(=O)C(C)(C)N(CCCCCCCCCSCCCC(F)(F)C(F)(F)F)C2=O)=CC=1C>>[NH2:35][C:32]1[CH:33]=[CH:34][C:29]([N:4]2[C:3](=[O:42])[C:2]([CH3:1])([CH3:43])[N:6]([CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][S:16]([CH2:18][CH2:19][CH2:20][C:21]([F:26])([F:27])[C:22]([F:25])([F:23])[F:24])=[O:17])[C:5]2=[O:28])=[CH:30][C:31]=1[CH3:38]

参加物

反応物 2

HCID 46945366HCID 46945366、化合物

HCID 46947540HCID 46947540、化合物

生成物 1

HCID 46945367HCID 46945367、化合物収率 56%

実験手順

The experimental protocol used is the same as that described for the synthesis of the compound of Example 2, the compound of Example 25 replacing the compound of Example 1. A colourless oil is obtained with a yield of 56%.

後処理

customA colourless oil is obtained with a yield of 56%

出典と根拠

ORDレコード: ord-9ee9407b94d642d89db6750a999d5ebe
出典データセット: uspto-grants-2014_04
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08710091B2

反応ノート

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