化工社化工社 化学情報印刷レポート · 研究参考用
Acetic Acid → 1,2,4-Triazolo(4,3-b)(1,2,4)triazine, 7-(4-chlorophenyl)-3-methyl-
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetic Acid | HCID 176 | — |
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | (4-Chlorophenyl)(oxo)acetaldehyde | HCID 269588 | — |
| 反応物 | HCID 13001264 | HCID 13001264 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 1,2,4-Triazolo(4,3-b)(1,2,4)triazine, 7-(4-chlorophenyl)-3-methyl- | HCID 3054502 | — |
反応手順
A solution of 7.8 g. of p-chlorophenylglyoxal, 6.3 g. of 3,4-diamino-5-methyl-4H-1,2,4-triazole hydrochloride and 1.7 g. of sodium hydroxide in 90 ml. of 67% acetic acid is heated on a steam bath for 1/2 hour. Water is added and heating is continued until yellow crystals separate. These crystals are collected by filtration and washed with hot ethanol, giving the desired product as a yellow solid, m.p. 240° C. (dec.).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04159375 |
| 出典データセット | uspto-grants-1979_06 |
| ORD ID | ord-e94de952614a40818e42d0c135ba6772 |
| 出典メモ | uspto-grants-1979_06 |