Acetic Acid → 1,2,4-Triazolo(4,3-b)(1,2,4)triazine, 7-(4-methoxyphenyl)-

HRID 237086ノート

反応式

HRID 237086 の反応式
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]([CH:11]=O)=O)=[CH:5][CH:4]=1.[NH2:13][C:14]1[N:18]([NH2:19])[CH:17]=[N:16][N:15]=1.C([O-])(=O)C.[Na+].C(O)(=O)C>O>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:11]=[N:19][N:18]3[CH:17]=[N:16][N:15]=[C:14]3[N:13]=2)=[CH:5][CH:4]=1

参加物

6

反応物 4

HCID 176Acetic AcidHCID 70643(4-Methoxyphenyl)glyoxalHCID 517045Sodium AcetateHCID 5671443,4-Diamino-1,2,4-triazole

生成物 1

HCID 30545031,2,4-Triazolo(4,3-b)(1,2,4)triazine, 7-(4-methoxyphenyl)-

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

A solution of 9.1 g. of p-methoxyphenylglyoxal, 6.7 g. of 3,4-diamino-4H-1,2,4-triazole and 4.1 g. of sodium acetate in 90 ml. of 67% acetic acid is heated on a steam bath for 1/2 hour. Water is added and heating is continued until crystals separate. The mixture is cooled and filtered. The precipitate is washed with water, ethanol and then hexane giving the desired product as yellow plates, m.p. 282.5°-284.5° C.

後処理

  1. temperatureheating
  2. customseparate
  3. temperatureThe mixture is cooled
  4. filtrationfiltered
  5. washThe precipitate is washed with water, ethanol

出典と根拠

ORDレコード
ord-3ee8d8310eaf43c7b4bc3e932185a9a1
出典データセット
uspto-grants-1979_06
特許番号
US04159375

反応ノート

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