Hydrazine → 5-(o-Fluorophenyl)-3-hydrazino-1,2,4-triazine

HRID 237092ノート

反応式

HRID 237092 の反応式
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[N:9]=[C:10](SC)[N:11]=[N:12][CH:13]=1.[NH2:16][NH2:17]>CO.O1CCCC1>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[N:9]=[C:10]([NH:16][NH2:17])[N:11]=[N:12][CH:13]=1

参加物

4

反応物 2

HCID 9321HydrazineHCID 125812725-(o-Fluorophenyl)-3-(methylthio)-1,2,4-triazine

生成物 1

HCID 125812735-(o-Fluorophenyl)-3-hydrazino-1,2,4-triazine

試薬・触媒・溶媒 1

HCID 21899815MeOH tetrahydrofuran溶媒

実験手順

To a solution of 27.6 g. of 5-(o-fluorophenyl)-3-(methylthio)-1,2,4-triazine in 100 ml. of 1:1 methanol-tetrahydrofuran is added 6.4 ml. of 95% hydrazine. The mixture is refluxed for about 22 hours and then cooled. The solid is recovered by filtration, giving 5-(o-fluorophenyl)-3-hydrazino-1,2,4-triazine as yellow crystals.

後処理

  1. temperatureThe mixture is refluxed for about 22 hours
  2. temperaturecooled
  3. filtrationThe solid is recovered by filtration

出典と根拠

ORDレコード
ord-0e9a25fb1dbd49919dcb5386f49b5240
出典データセット
uspto-grants-1979_06
特許番号
US04159375

反応ノート

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