5-(o-Fluorophenyl)-3-hydrazino-1,2,4-triazine → 7-(o-Fluorophenyl)-3-methyl-1,2,4-triazolo[4,3-b]-1,2,4-triazine

HRID 237093ノート

反応式

HRID 237093 の反応式
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[N:9]=[C:10]([NH:14][NH2:15])[N:11]=[N:12][CH:13]=1.[C:16]([O-])([O-])(OCC)[CH3:17]>>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[CH:13]=[N:12][N:11]2[C:16]([CH3:17])=[N:15][N:14]=[C:10]2[N:9]=1

参加物

3

反応物 2

HCID 125812735-(o-Fluorophenyl)-3-hydrazino-1,2,4-triazineHCID 86598186Ethyl ortho-acetate

生成物 1

HCID 125812757-(o-Fluorophenyl)-3-methyl-1,2,4-triazolo[4,3-b]-1,2,4-triazine

実験手順

A mixture of 6.15 g. of 5-(o-fluorophenyl)-3-hydrazino-1,2,4-triazine and 50 ml. of ethyl orthoacetate is refluxed for 2.5 hours, cooled and the solid is collected by filtration and washed with hexane and ethanol, giving the desired product as yellow crystals, m.p. 227°-229° C.

後処理

  1. additionA mixture of 6.15 g
  2. temperaturecooled
  3. filtrationthe solid is collected by filtration
  4. washwashed with hexane and ethanol

出典と根拠

ORDレコード
ord-8993d7c1ae9a4ce490a33fcb8a92ee1c
出典データセット
uspto-grants-1979_06
特許番号
US04159375

反応ノート

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