3-Hydrazino-5-(alpha,alpha,alpha-trifluoro-m-tolyl)-1,2,4-triazine → 3-Methyl-7-(alpha,alpha,alpha-trifluoro-m-tolyl)-1,2,4-triazolo[4,3-b]-1,2,4-triazine
反応式
[NH:1]([C:3]1[N:4]=[N:5][CH:6]=[C:7]([C:9]2[CH:10]=[C:11]([C:15]([F:18])([F:17])[F:16])[CH:12]=[CH:13][CH:14]=2)[N:8]=1)[NH2:2].[C:19]([O-])([O-])(OCC)[CH3:20]>>[CH3:19][C:20]1[N:4]2[N:5]=[CH:6][C:7]([C:9]3[CH:10]=[C:11]([C:15]([F:18])([F:17])[F:16])[CH:12]=[CH:13][CH:14]=3)=[N:8][C:3]2=[N:1][N:2]=1参加物
3
実験手順
A mixture of 5.1 g. of 3-hydrazino-5-(α,α,α-trifluoro-m-tolyl)-1,2,4-triazine and 60 ml. of ethyl orthoacetate is refluxed for 2.5 hours, cooled and the solid is collected by filtration and washed with hexane and ethanol, giving the desired product as yellow plates, m.p. 230°-233° C.
後処理
- additionA mixture of 5.1 g
- temperaturecooled
- filtrationthe solid is collected by filtration
- washwashed with hexane and ethanol
出典と根拠
- ORDレコード
- ord-2dd4cbfef74441868ce96f157b218423
- 出典データセット
- uspto-grants-1979_06
- 特許番号
- US04159375
反応ノート
読み込み中…