化工社化工社 化学情報印刷レポート · 研究参考用
Ethanol → (1S)-1-phenylethanaminium
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethanol | HCID 702 | — |
| 反応物 | 2,3-Dihydroxybutanedioic Acid | HCID 875 | — |
| 反応物 | 1-Phenethylamine, (-)- | HCID 75818 | — |
| 生成物 | (1S)-1-phenylethanaminium | HCID 7855572 | — |
| 生成物 | (+)-(1R,2S,3R)-3-hydroxy-2-pentyl-1-cyclopentaneacetic acid | HCID 11171909 | — |
| 生成物 | (1R,2S,3R)-3-hydroxy-2-pentyl-1-cyclopentaneacetate | HCID 131720568 | — |
反応手順
This acid presented the analytical characters of the racemic acid described under b) and a [α]20D =-12° (c=1.15, ethanol) (purity: 99%; e.r. 99.2:0.8). Proceeding in a manner analogous to that described here-above, but using (-)-(S)-1-penylethylamine (Fluka purum; e.r. 98:2), there was obtained (1R,2S,3R)-3-hydroxy-2-pentyl-1-cyclopentaneacetate of (S)-1-phenyl-ethylammonium (m.p. 131°-132°; [α]20D =+4°; c=1.05, ethanol) and (+)-(1R,2S,3R)-3-hydroxy-2-pentyl-1-cyclopentaneacetic acid having [α]20D =+11° (c=1.10, ethanol) (purity: 99%; e.r. 96.5:3.5).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05728866 |
| 出典データセット | uspto-grants-1998_03 |
| ORD ID | ord-9351ff791ece43d89068d7c5e43ad1d4 |
| 出典メモ | uspto-grants-1998_03 |