化工社化工社 化学情報印刷レポート · 研究参考用
Sulfuric Acid → 5-Amino-2-methoxybenzoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sulfuric Acid | HCID 1118 | — |
| 反応物 | 5-Aminosalicylic Acid | HCID 4075 | — |
| 反応物 | Sodium Carbonate | HCID 10340 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 5-Amino-2-methoxybenzoic acid | HCID 13549244 | — |
反応手順
A solution of 10 g of 5-aminosalicyclic acid, 100 ml of methanol and 5 ml of sulfuric acid are refluxed overnight. The reaction mixture is cooled, basified with sodium carbonate and the methanol is evaporated. The resulting solid is washed with water and dried giving 4.0 g of methyl-5-aminosalicylic acid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04159384 |
| 出典データセット | uspto-grants-1979_06 |
| ORD ID | ord-0bc782b352414c98ba5f6e110eaba258 |
| 出典メモ | uspto-grants-1979_06 |