Hydrazine → HCID 67905363、化合物

HRID 2371421ノート

反応式

HRID 2371421 の反応式
[NH2:1][NH2:2].[O:3]=[C:4]1[CH:9]([CH2:10][C:11](OC)=[O:12])[S:8](=[O:16])(=[O:15])[C:7]2[S:17][C:18]([S:20](=[O:23])(=[O:22])[NH2:21])=[CH:19][C:6]=2[NH:5]1>CO>[S:20]([C:18]1[S:17][C:7]2[S:8](=[O:16])(=[O:15])[CH:9]([CH2:10][C:11]([NH:1][NH2:2])=[O:12])[C:4](=[O:3])[NH:5][C:6]=2[CH:19]=1)(=[O:23])(=[O:22])[NH2:21]

参加物

4

反応物 2

HCID 9321HydrazineHCID 86745510HCID 86745510、化合物

生成物 1

HCID 67905363HCID 67905363、化合物

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

Anhydrous hydrazine (1 ml) was added to a solution of methyl (2,3-dihydro-2,4,4-trioxo-6-sulfamoyl-1H-thieno[2,3-b][1,4]thiazin-3-yl)acetate (1.0 g) in methanol (10 ml) at ambient temperature with stirring. After 5-6 hours, the methanol was removed under reduced pressure and the residue was treated with water (10 ml). The pH was adjusted to 6.5 and the resulting precipitate was collected, rinsed with water and dried under vacuum to give 0.40 g (2,3-dihydro-6-sulfamoyl-2,4,4-trioxo-1H-thieno[2,3-b][1,4]thiazin-3-yl)acetic acid hydrazide, mp 230° C., dec.

後処理

  1. customthe methanol was removed under reduced pressure
  2. additionthe residue was treated with water (10 ml)
  3. customthe resulting precipitate was collected
  4. washrinsed with water
  5. customdried under vacuum

出典と根拠

ORDレコード
ord-17f5911b7ee34a7c88cb981e686592f3
出典データセット
uspto-grants-1992_03
特許番号
US05093332

反応ノート

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