Sodium Nitrite → HCID 19907222、化合物

HRID 2371422ノート

反応式

HRID 2371422 の反応式
[N:1]([O-])=O.[Na+].[S:5]([C:9]1[S:25][C:12]2[S:13](=[O:24])(=[O:23])[CH:14]([CH2:18][C:19]([NH:21][NH2:22])=[O:20])[C:15](=[O:17])[NH:16][C:11]=2[CH:10]=1)(=[O:8])(=[O:7])[NH2:6]>O.Cl>[O:17]=[C:15]1[CH:14]([CH2:18][C:19]([N:21]=[N+:22]=[N-:1])=[O:20])[S:13](=[O:23])(=[O:24])[C:12]2[S:25][C:9]([S:5](=[O:7])(=[O:8])[NH2:6])=[CH:10][C:11]=2[NH:16]1

参加物

5

反応物 2

HCID 23668193Sodium NitriteHCID 67905363HCID 67905363、化合物

生成物 1

HCID 19907222HCID 19907222、化合物収率 57.5%

試薬・触媒・溶媒 2

HCID 313Hydrochloric Acid溶媒HCID 962Water溶媒

実験手順

A solution of sodium nitrite (0.34 g, 5 mmol) in water (10 ml) was added slowly to a cold (0°-5° C. suspension of (2,3-dihydro-6-sulfamoyl-2,4,4-trioxo-1H-thieno[2,3-b][1,4]thiazin-3-yl)acetic acid hydrazide (1.75 g, 5 mmol) in 1N HCl (150 ml). The reaction mixture was stirred for 0.5 hours in the cold and the resulting solid was collected, rinsed with water and air-dried to yield 1.05 g (2,3-dihydro-2,4,4-trioxo-6-sulfamoyl-1H-thieno-[2,3-b][1,4]thiazin-3-yl)acetyl azide.

後処理

  1. customwas collected
  2. washrinsed with water
  3. customair-dried

出典と根拠

ORDレコード
ord-90dda8f688e34e06a441b6238f8a9469
出典データセット
uspto-grants-1992_03
特許番号
US05093332

反応ノート

読み込み中…