Water → 3-benzyl-2-[(N-cyclohexylcarbamoyl)-imino]benzothiazole

HRID 2371703

反応式

HRID 2371703 の反応式
[CH2:1]([N:8]1[C:12]2[CH:13]=[CH:14][CH:15]=[CH:16][C:11]=2[S:10][C:9]1=[NH:17])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C([O-])(=O)CCCCCCCCCCC.C([O-])(=O)CCCCCCCCCCC.C([Sn+2]CCCC)CCC.[CH:55]1([N:61]=[C:62]=[O:63])[CH2:60][CH2:59][CH2:58][CH2:57][CH2:56]1.O>CC(C)=O>[CH2:1]([N:8]1[C:12]2[CH:13]=[CH:14][CH:15]=[CH:16][C:11]=2[S:10][C:9]1=[N:17][C:62](=[O:63])[NH:61][CH:55]1[CH2:60][CH2:59][CH2:58][CH2:57][CH2:56]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

参加物

6

反応物 4

HCID 962WaterHCID 18502Cyclohexyl isocyanateHCID 6775663-Benzyl-2-iminobenzothiazoleHCID 9809426Di-n-butyldilauryltin

生成物 1

HCID 544673103-benzyl-2-[(N-cyclohexylcarbamoyl)-imino]benzothiazole収率 73.1%

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

To a solution of 1.8 g of 3-benzyl-2-iminobenzothiazole and a catalytic amount of dibutyltin dilaurate in 30 ml of acetone was added 0.95 g of cyclohexyl isocyanate dropwise. After seven hours, the reaction mixture was poured into approximately 100 ml of water. The crystals precipitated were collected by filtering to thereby obtain 2.0 g of the objective compound.

後処理

  1. customThe crystals precipitated
  2. customwere collected
  3. filtrationby filtering

出典と根拠

ORDレコード
ord-0e6b3d4aa3dc4c98960b65ff1deb1b73
出典データセット
uspto-grants-1992_03
特許番号
US05095025

関連ノート

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