Dimethylamine → HCID 57271419、化合物

HRID 2372382ノート

反応式

HRID 2372382 の反応式
[CH:1]([O:4][C:5]([C:7]1[CH:8]([CH3:28])[CH2:9][N:10]2[C:14](=[CH:15][C:16]([O:18]C3C=CC([N+]([O-])=O)=CC=3)=O)[CH2:13][S:12][C:11]=12)=[O:6])([CH3:3])[CH3:2].[CH3:29][NH:30][CH3:31]>O>[CH3:29][N:30]([CH3:31])[C:16](=[O:18])[CH:15]=[C:14]1[CH2:13][S:12][C:11]2=[C:7]([C:5]([O:4][CH:1]([CH3:2])[CH3:3])=[O:6])[CH:8]([CH3:28])[CH2:9][N:10]12

参加物

4

反応物 2

HCID 674DimethylamineHCID 867455674-Nitrophenyl (7-Isopropoxycarbonyl-6-methyl-2,3,5,6-tetrahydropyrrolo[2,1-b]thiazol-3-ylidene)acetate

生成物 1

HCID 57271419HCID 57271419、化合物

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

To 1.50 g of 4-nitrophenyl (7-isopropoxycarbonyl-6-methyl-2,3,5,6-tetrahydropyrrolo[2,1-b]thiazol-3-ylidene)acetate, was added 40 ml of a 25% aqueous solution of dimethylamine and the mixture was stirred at room temperature for 3 days. 40 ml of water was added thereto and the precipitate thus formed was collected by filtration, washed with water and dissolved in chloroform. After drying and distilling off the solvent, the crude crystals thus obtained were recrystallized from a solvent mixture of ether and n-hexane. Thus 0.6 g of the title compound was obtained.

後処理

  1. customthe precipitate thus formed
  2. filtrationwas collected by filtration
  3. washwashed with water
  4. dissolutiondissolved in chloroform
  5. customAfter drying
  6. distillationdistilling off the solvent
  7. customthe crude crystals thus obtained
  8. customwere recrystallized from a solvent mixture of ether and n-hexane

出典と根拠

ORDレコード
ord-62dd0dd976584d1f8d41b8de28be302a
出典データセット
uspto-grants-1992_03
特許番号
US05098919

反応ノート

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