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Ethylenediamine → p-Hydroxymethylbenzoylaminoethylamine acetate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethylenediamine | HCID 3301 | — |
| 反応物 | Ethyl 4-(hydroxymethyl)benzoate | HCID 12480307 | — |
| 生成物 | p-Hydroxymethylbenzoylaminoethylamine acetate | HCID 67918850 | 49% |
反応手順
Ethyl p- hydroxymethylbenzoate (0.51 g, 2.8 mmol) was dissolved in ethylene diamine and heated on a steam bath overnight. The volume was reduced under a stream of nitrogen and the residue was chromatographed by preparative thin layer chromatography (silica, CHCl3 : MeOH:HOAc, 10:10:1) to yield the product as an oil (0.35 g, 49% yield).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05098996 |
| 出典データセット | uspto-grants-1992_03 |
| ORD ID | ord-a191819783a74eb5b51fd002fccb8f73 |
| 出典メモ | uspto-grants-1992_03 |