化工社化工社 化学情報印刷レポート · 研究参考用
Dimethylformamide → 4-Chloro-7-nitroquinazoline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Dimethylformamide | HCID 6228 | — |
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | 7-Nitroquinazolin-4(3H)-one | HCID 86222800 | — |
| 生成物 | 4-Chloro-7-nitroquinazoline | HCID 830680 | — |
反応手順
To a solution of 7-nitroquinazolin-4(3H)-one (2.0 g, 10.5 mmol) in 40 ml thionyl chloride was added 0.8 ml of DMF and the mixture was heated at reflux overnight then evaporated to dryness to provide crude 4-chloro-7-nitroquinazoline.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08642582B2 |
| 出典データセット | uspto-grants-2014_02 |
| ORD ID | ord-f0f7d6401cd4487e98e4fe40bbd46dba |
| 出典メモ | uspto-grants-2014_02 |