化工社化工社 化学情報印刷レポート · 研究参考用
Ammonia → 7-Nitroquinazolin-4-amine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ammonia | HCID 222 | — |
| 反応物 | 4-Chloro-7-nitroquinazoline | HCID 830680 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 7-Nitroquinazolin-4-amine | HCID 13697798 | — |
反応手順
A mixture of 1.6 g of 4-chloro-7-nitroquinazoline in 50 ml 7N ammonia in methanol was stirred overnight at rt and concentrated to dryness. The solid was suspended in water, filtered, rinsed with water followed by ether and dried overnight in vacuum oven to provide 0.98 g of 7-nitroquinazolin-4-amine (Compound 98-2).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08642582B2 |
| 出典データセット | uspto-grants-2014_02 |
| ORD ID | ord-9c94a77e0d38476da509652811c7b21c |
| 出典メモ | uspto-grants-2014_02 |