1-(4-Iodophenyl)ethan-1-one → 1-[4-(3,3-Dimethyl-3,4-dihydro-2H-benzo[b][1,4]dioxepin-7-ylethynyl)-phenyl]-ethanone

HRID 2373443

反応式

HRID 2373443 の反応式
[C:1]([C:3]1[CH:15]=[CH:14][C:6]2[O:7][CH2:8][C:9]([CH3:13])([CH3:12])[CH2:10][O:11][C:5]=2[CH:4]=1)#[CH:2].I[C:17]1[CH:22]=[CH:21][C:20]([C:23](=[O:25])[CH3:24])=[CH:19][CH:18]=1>>[CH3:13][C:9]1([CH3:12])[CH2:8][O:7][C:6]2[CH:14]=[CH:15][C:3]([C:1]#[C:2][C:17]3[CH:22]=[CH:21][C:20]([C:23](=[O:25])[CH3:24])=[CH:19][CH:18]=3)=[CH:4][C:5]=2[O:11][CH2:10]1

参加物

3

反応物 2

HCID 728691-(4-Iodophenyl)ethan-1-oneHCID 598526957-Ethynyl-3,3-dimethyl-3,4-dihydro-2H-benzo[b][1,4]dioxepine

生成物 1

HCID 598526931-[4-(3,3-Dimethyl-3,4-dihydro-2H-benzo[b][1,4]dioxepin-7-ylethynyl)-phenyl]-ethanone

実験手順

The title compound is prepared in analogy to example 1 from 7-ethynyl-3,3-dimethyl-3,4-dihydro-2H-benzo[b][1,4]dioxepine (6) (example 1d) and 1-(4-iodo-phenyl)-ethanone. MS (ESI) 320.2 (M•)+.

出典と根拠

ORDレコード
ord-fbe8ec5045bd41b1b9a90e85259d1044
出典データセット
uspto-grants-2008_12
特許番号
US07459480B2

関連ノート

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