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{(S)-6-[(R)-4-bromo-7-fluoro-indan-1-yloxy]-2,3-dihydro-benzofuran-3-yl}-acetic acid methyl ester → ((S)-6-{(R)-7-Fluoro-4-[4-(2-hydroxy-2-methyl-propylcarbamoyl)-2,6-dimethyl-phenyl]indan-1-yloxy}-2,3-dihydro-benzofuran-3-yl)-acetic acid methyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | {(S)-6-[(R)-4-bromo-7-fluoro-indan-1-yloxy]-2,3-dihydro-benzofuran-3-yl}-acetic acid methyl ester | HCID 86697103 | — |
| 反応物 | 4-bromo-N-(2-hydroxy-2-methyl-propyl)-3,5-dimethyl-benzamide | HCID 86697188 | — |
| 生成物 | ((S)-6-{(R)-7-Fluoro-4-[4-(2-hydroxy-2-methyl-propylcarbamoyl)-2,6-dimethyl-phenyl]indan-1-yloxy}-2,3-dihydro-benzofuran-3-yl)-acetic acid methyl ester | HCID 86697187 | — |
反応手順
The title compound is prepared following a procedure analogous to that described in Step 5 in the preparation of Intermediate 1, starting from 4-bromo-N-(2-hydroxy-2-methyl-propyl)-3,5-dimethyl-benzamide.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08642585B2 |
| 出典データセット | uspto-grants-2014_02 |
| ORD ID | ord-62f3b4a34b2d4b879b0bca427d828b9a |
| 出典メモ | uspto-grants-2014_02 |