化工社化工社 化学情報印刷レポート · 研究参考用
4-Amino-2,6-dibromophenol → ethyl 1-(3,5-dibromo-4-hydroxyphenyl)-2,5-dimethyl-1H-pyrrole-3-carboxylate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Amino-2,6-dibromophenol | HCID 69107 | — |
| 反応物 | Ethyl 2-acetyl-4-oxovalerate | HCID 3084847 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | ethyl 1-(3,5-dibromo-4-hydroxyphenyl)-2,5-dimethyl-1H-pyrrole-3-carboxylate | HCID 69274007 | — |
反応手順
Utilizing the procedure outlined in Example 85, ethyl 2-acetyl-4-oxopentanoate (6.37 g, 34.2 mmol) was dissolved in 20 mL of EtOH. 2,6-dibromo-4-aminophenol (11.6g, 34.2mmol) were reacted to afford ethyl 1-(3,5-dibromo-4-hydroxyphenyl)-2,5-dimethyl-1H-pyrrole-3-carboxylate was taken on without further purification. MS (ESI) 418 (M+H)+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07465730B2 |
| 出典データセット | uspto-grants-2008_12 |
| ORD ID | ord-d3768bf0effa473a8e30a37b8c51e892 |
| 出典メモ | uspto-grants-2008_12 |