MeOH tetrahydrofuran → HCID 23113862、化合物

反応式

[Br:1][C:2]1[C:12](C)=[CH:11]C(OCC(C)=O)=[C:4]([CH2:14][C:15]2[CH:20]=[CH:19][C:18]([CH:21]([CH3:23])[CH3:22])=[CH:17][CH:16]=2)[C:3]=1[CH3:24].[CH3:25]O.[CH2:27]1[CH2:31][O:30][CH2:29][CH2:28]1>>[Br:1][C:2]1[C:3]([CH3:24])=[C:4]([CH2:14][C:15]2[CH:20]=[CH:19][C:18]([CH:21]([CH3:23])[CH3:22])=[CH:17][CH:16]=2)[C:31]2[O:30][CH:29]=[C:28]([CH3:25])[C:27]=2[C:12]=1[CH3:11]

参加物

反応物 2

HCID 21899815MeOH tetrahydrofuran

HCID 23114331HCID 23114331、化合物

生成物 1

HCID 23113862HCID 23113862、化合物収率 84%

実験手順

Using 1-(4-bromo-1-(2-(4-isopropylbenzyl)-3,5-dimethylphenoxy)acetone obtained in Reference Example 189, the title compound was synthesized in the same manner as in Reference Example 143. Yield 84%. Melting point: 76-77° C. (methanol-THF).

後処理

customobtained in Reference Example 189

出典と根拠

ORDレコード: ord-ec82db65cdd04d4d865a6d9756abca62
出典データセット: uspto-grants-2008_12
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07465815B2

反応ノート

読み込み中…