3-Iodophthalic acid → 3-Iodophthalic anhydride

HRID 2377014

反応式

HRID 2377014 の反応式
[I:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:4]([C:5]([OH:7])=O)[C:3]=1[C:11]([OH:13])=[O:12]>C(OC(=O)C)(=O)C>[I:1][C:2]1[C:3]2[C:11](=[O:12])[O:13][C:5](=[O:7])[C:4]=2[CH:8]=[CH:9][CH:10]=1

参加物

3

反応物 1

HCID 2382313-Iodophthalic acid

生成物 1

HCID 2820713-Iodophthalic anhydride収率 65.2%

試薬・触媒・溶媒 1

HCID 7918Acetic Anhydride溶媒

実験手順

A solution of 3-iodophthalic acid (0.9 g, 3.08 mmol) in acetic anhydride (5 mL) was heated to reflux under nitrogen overnight. After cooling, the solvent was removed in vacuo and the residue purified by trituration with ethanol to give 4-iodo-2-benzofuran-1,3-dione (0.55 g, 65%).

後処理

  1. temperatureto reflux under nitrogen overnight
  2. temperatureAfter cooling
  3. customthe solvent was removed in vacuo
  4. customthe residue purified by trituration with ethanol

出典と根拠

ORDレコード
ord-06b41cd4add44d28838ce483980247c8
出典データセット
uspto-grants-2008_12
特許番号
US07468393B2

関連ノート

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